The two numbers clinics quote, decoded
Marketing pages tend to cite one of two figures without saying what it measured.| Claim you will see | What it actually measured |
|---|---|
| "~80% success" | Short-term relief of acute opioid withdrawal within days, which is genuinely common in the cohorts studied. It is not a measure of staying clean. |
| "~30% success" | Closer to the share still abstinent months later after a single treatment. Longer-term abstinence is the harder and more honest metric. |
What the prospective data shows
The best real-world data comes from prospective observational cohorts, not randomized trials. In a New Zealand cohort that followed opioid-dependent patients after a single ibogaine treatment, a meaningful subset showed sustained reductions in use at 12 months, with outcomes strongest among those who did not relapse early.[1] A larger case series similarly reported rapid withdrawal relief and reduced cravings, with durability varying widely.[2] The signal is real. The precision a "success rate" implies is not there yet.Why no honest single number exists
Three reasons. First, no completed randomized controlled trial: without a control group you cannot separate the drug's effect from expectation, setting and the aftercare people pursued. Second, "success" is defined differently in every study (withdrawal relief, reduced use, complete abstinence). Third, follow-up is hard in this population, and people lost to follow-up are often those doing worst, which flatters the numbers that remain. The Texas IMPACT trial funded in 2025 is designed partly to produce the controlled data that would finally support a real figure.[3]What this means for you
- Treat any clinic quoting a single high "success rate" with skepticism, and ask what it measured and over what time period.
- Judge a program partly by how seriously it takes aftercare, because sustained outcomes track with it more than with the dose alone.
- If durable, controlled proof is your bar, that data does not exist yet. Weigh the decision as an early, promising intervention, not a proven cure.
Sources
Reviewed against primary literature and updated July 2026. This is information, not medical advice.